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Extra resources for Antigens, Lymphoid Cells and the Immune Response

Example text

The F c fragment of immunoglobulins contains carbohydrate residues and intrachain disulfide groups. That the latter may play a role (such as a disulfide bond interchange) is suggested by Benacerrafs observa­ tions that the reaction of antibody with macrophages is weakened by the prior reduction and alkylation of the antibody molecule. On the other hand, this effect may simply be due to a change in conformation of the antibody molecule, in which case the disulfide bonds would play an indirect rather than a direct role.

4 ) Antigens may be retained in lymphoid tissues for varying lengths of time. 0035 Popliteal nodes - These animals were not fed carrier iodide in their drinking water. 4 Lung Lang and Ada (1967a) Ada and Lang (1966) Ada and Williams (1966) Ada et al. (1964b) Ada et al. (1964b) Humphrey and Frank (1967) Reference THE PROPORTION OF RADIOACTIVITY PRESENT AT THE INJECTION SITE AND IN DIFFERENT TISSUES AFTER HIND FOOTPAD INJECTION OF VARIOUS PROTEINS LABELED WITH 1261 OR 131I INTO RATS OR RABBITS 46 4 .

0035 Popliteal nodes - These animals were not fed carrier iodide in their drinking water. 4 Lung Lang and Ada (1967a) Ada and Lang (1966) Ada and Williams (1966) Ada et al. (1964b) Ada et al. (1964b) Humphrey and Frank (1967) Reference THE PROPORTION OF RADIOACTIVITY PRESENT AT THE INJECTION SITE AND IN DIFFERENT TISSUES AFTER HIND FOOTPAD INJECTION OF VARIOUS PROTEINS LABELED WITH 1261 OR 131I INTO RATS OR RABBITS 46 4 . Organ Distribution of Antigens gated before injection, is detected in the draining lymph node after footpad injection for a period of only a few days after injection.

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